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ORIGINAL RESEARCH article

Front. Pediatr.
Sec. Children and Health
Volume 12 - 2024 | doi: 10.3389/fped.2024.1503926

Anthocyanin intake and myopia in adolescents

Provisionally accepted
Ying Chen Ying Chen 1Qinglin Xu Qinglin Xu 1Lu Lv Lu Lv 2Yun Liu Yun Liu 2Zhidan Zhang Zhidan Zhang 2Zhikuan Yang Zhikuan Yang 1*
  • 1 Aier Eye Hospital of Jinan, Jinan, China
  • 2 Wuhan Aier Eye Hospital, Wuhan, Hebei Province, China

The final, formatted version of the article will be published soon.

    The study aimed to explore the relationship of anthocyanin and its subtypes with myopia in adolescents aged 12-17 years.Methods: Adolescents data for this cross-sectional study were extracted from the National Health and Nutrition Examination Survey (NHANES) 2007-2008. Anthocyanin and subtypes were obtained using the Nutrient Database for Dietary Studies codes. Myopia was defined as a spherical equivalent of -1.0 diopters or less.The relationships between anthocyanin and subtypes intake and myopia were determined utilizing weighted univariate and multivariate logistic regression models.The relationships were also explored in gender, leisure time, physical activity, sedentary activity, BMI, and serum cotinine subgroups.Results: A total of 839 adolescents were included for further analysis, among them 245 have myopia. Malvidin (34.98%) was the subtype with the largest anthocyanin intake, followed by cyanidin (22.94%). Compared to adolescents without anthocyanin intake, total anthocyanin intake was related to a lower incidence of myopia (OR=0.69, 95%CI: 0.51-0.92). Higher intake of cyanidin (OR=0.69, 95%CI: 0.52-0.92), petunidin (OR=0.64, 95%CI: 0.42-0.97), and delphinidin (OR=0.71, 95%CI: 0.51-0.99) were associated with lower odds of myopia in adolescents. Higher total anthocyanin intake was related to lower odds of myopia in those females, leisure time physical activity ≥60 min/day, sedentary time <8 hours/day, overweight or obese, and serum cotinine ≥0.05 ng/ml.Higher total anthocyanin intake, particularly cyanidin, petunidin, and Anthocyanin intake and myopia in adolescents 4 delphinidin, was related to a lower incidence of myopia in adolescents. Increasing 48 dietary anthocyanin intake may be an effective prevention strategy for ocular health.

    Keywords: Adolescent, Myopia, adolescents, Cyanidin, Petunidin, Delphinidin

    Received: 30 Sep 2024; Accepted: 31 Oct 2024.

    Copyright: © 2024 Chen, Xu, Lv, Liu, Zhang and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhikuan Yang, Aier Eye Hospital of Jinan, Jinan, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.