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ORIGINAL RESEARCH article

Front. Pediatr.
Sec. Pediatric Rheumatology
Volume 12 - 2024 | doi: 10.3389/fped.2024.1487080
This article is part of the Research Topic Promoting Patient-Centered Care for Pediatric Rheumatology Across Africa View all 5 articles

Predictors of musculoskeletal pain among hemodialysis children

Provisionally accepted
Doaa Mosad Mosa Doaa Mosad Mosa 1*Mohamed Taman Mohamed Taman 2Doaa Shokry Alemam Doaa Shokry Alemam 3Mohamed M Zedan Mohamed M Zedan 4Mai S Korkor Mai S Korkor 5
  • 1 Department of Physical Medicine, Rheumatology& Rehabilitation, Mansoura University Hospitals, Mansoura University Faculty of Medicine, Mansoura University, Mansoura, Egypt
  • 2 Department of Obstetrics and Gynecology, Mansoura University Hospital, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt
  • 3 Department of Public health and Community Medicine, Faculty of Medicine, Mansoura University,, Mansoura University, Mansoura, Egypt
  • 4 Department of Pediatrics, Mansoura University Children’s Hospital, Mansoura University Faculty of Medicine,, Mansoura University, Mansoura, Egypt
  • 5 Department of Pediatrics, Mansoura University Children’s Hospital, Mansoura University Faculty of Medicine, Mansoura University, Mansoura, Egypt

The final, formatted version of the article will be published soon.

    Background: Children who undergoing haemodialysis are vulnerable to musculoskeletal (MSK) abnormalities. These conditions can potentially lead to functional impairments. Hence, this study was to explore the prevalence of MSK disorders in haemodialysis children and predicting factors associated with these manifestations. Method: This cross sectional study was conducted on a group of children undergoing haemodialysis at the nephrology unit, Mansoura University Children's Hospital (MUCH) from December 2022 till January 2024. Patient demographics, clinical, musculoskeletal findings, physical function, and quality of life assessment parameters were collected. Besides, laboratory data and dual energy X-ray absorptiometry (DEXA). All patients were classified according to the presence of MSK pain into two groups, group A: with MSK pain and group B: without MSK pain. Results: The total number of cases with MSK manifestations were 32 (64%). The most frequent musculoskeletal manifestations were: osteoporosis/osteopenia (64%), myalgia (64%), cramps (60%), arthralgia/arthritis (32%), regional pain (32%). MSK pain was independently associated with longer dialysis duration, the presence of comorbidity, childhood-health assessment questionnaire (C-HAQ), Paediatric Quality of Life Inventory (Peds-QL), hemoglobin level, serum uric acid, the calcium × phosphate product, and DEXA (Z-score). Conclusion: Involvement of MSK system is a common morbidity in children with hemodialysis. Calcium × phosphate product and vitamin D level were the most significant predictors of MSK pain.

    Keywords: predictors, Musculoskeletal Pain, hemodialysis, Children, joint pain

    Received: 27 Aug 2024; Accepted: 31 Dec 2024.

    Copyright: © 2024 Mosa, Taman, Alemam, Zedan and Korkor. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Doaa Mosad Mosa, Department of Physical Medicine, Rheumatology& Rehabilitation, Mansoura University Hospitals, Mansoura University Faculty of Medicine, Mansoura University, Mansoura, Egypt

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.