Skip to main content

CASE REPORT article

Front. Pediatr.
Sec. Pediatric Oncology
Volume 12 - 2024 | doi: 10.3389/fped.2024.1460251

A Rare Case of Antenatally Diagnosed Mature Adrenal Teratoma in an Infant: Insights and Literature Review

Provisionally accepted
Amar Msarweh Amar Msarweh 1*Mohammad Hakam Shehadeh Mohammad Hakam Shehadeh 1,2*Ahmad M Abualrub Ahmad M Abualrub 1Waleed M Malhes Waleed M Malhes 1Nadeen Msarweh Nadeen Msarweh 1Jenan Khaled Sinokrot Jenan Khaled Sinokrot 1Ahmed H Aliwisat Ahmed H Aliwisat 3
  • 1 Faculty of Medicine, Al-Quds University, Jerusalem, Palestine, Jerusalem, Palestine
  • 2 Al-Quds University, Jerusalem, Palestine
  • 3 Department of Pediatric Surgery, Al-Makassed Islamic Charitable Hospital, Jerusalem, Palestine, Jerusalem, Palestine

The final, formatted version of the article will be published soon.

    Teratomas are germ cell tumors that arise from the derivatives of the three germ cell layers. They are categorized into subtypes by the extent of maturation, with mature teratomas being the most common subtype. While they can arise in various extragonadal regions, including the retroperitoneum, their occurrence in the retroperitoneal space is extremely rare. It is even more exceptional for these tumors to be located within the adrenal gland. In this report, we describe an 18-day-old female infant who presented with a left suprarenal mass. The mass was detected during prenatal screening via ultrasound at 30 weeks of pregnancy. Evaluation after birth, including a chest and abdomen computed tomography (CT) scan, revealed a large, well-defined left suprarenal mass. The mass was surgically resected and found to measure 9 cm x 7 cm × 5 cm. Histopathological examination confirmed a cystic mature teratoma containing a variety of well-differentiated tissues. The patient has shown excellent progress over the 1-year follow-up, with no evidence of recurrence. Only a few cases of mature adrenal teratoma have been reported, highlighting the importance of this case report.

    Keywords: Teratoma, adrenal gland, Mature teratoma, Retroperitoneal, Prenatal screening

    Received: 05 Jul 2024; Accepted: 06 Nov 2024.

    Copyright: © 2024 Msarweh, Shehadeh, Abualrub, Malhes, Msarweh, Sinokrot and Aliwisat. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Amar Msarweh, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine, Jerusalem, Palestine
    Mohammad Hakam Shehadeh, Al-Quds University, Jerusalem, Palestine

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.