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ORIGINAL RESEARCH article

Front. Pediatr.
Sec. Pediatric Surgery
Volume 12 - 2024 | doi: 10.3389/fped.2024.1457927

Gallbladder Preserving Cholelithotomy in Children with Hereditary Spherocytosis Complicated by Gallstones: A single-center retrospective study

Provisionally accepted
Ran Tang Ran Tang Cheng-xiao Zhou Cheng-xiao Zhou Yong Yang Yong Yang Jian Bian Jian Bian Li-xiang Meng Li-xiang Meng De-cheng Wei De-cheng Wei Shiqin Qi Shiqin Qi *
  • Anhui Provincial Children’s Hospital, Hefei, China

The final, formatted version of the article will be published soon.

    Background: Gallstones are among the most common complications of hereditary spherocytosis (HS). In previous treatments, gallbladder-preserving cholelithotomy (GPC) has remained a subject of significant debate due primarily to potential risks of stone recurrence. However, past studies have often overlooked the impact of specific disease conditions on GPC. In this study, we reviewed the clinical data of GPC in HS pediatric patients with concurrent gallstones over a period of seven years in a single center.From December 2016 to April 2024, 32 pediatric patients with HS who underwent splenectomy and GPC surgery based on our inclusion criteria. Clinical pathological, and follow-up data of these patients were collected.Results: In terms of short-term complications, there were there were no cases of postoperative bleeding, bile duct injury. 3 cases (9.3%) experienced varying degrees of bile peritonitis. During long-term follow-up, only 2 cases (6.2%) showed recurrence of gallstones. One case of bile leakage occurred. Conclusion:GPC demonstrates significant efficacy for pediatric patients with hereditary spherocytosis (HS) complicated by gallstones, showing a a low recurrence rate and high safety profile.

    Keywords: :gallbladder-preserving cholelithotomy, pediatric, Hereditary spherocytosis, Surgery, Choledochoscope

    Received: 01 Jul 2024; Accepted: 31 Oct 2024.

    Copyright: © 2024 Tang, Zhou, Yang, Bian, Meng, Wei and Qi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Shiqin Qi, Anhui Provincial Children’s Hospital, Hefei, China

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