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CASE REPORT article

Front. Pediatr.
Sec. Neonatology
Volume 12 - 2024 | doi: 10.3389/fped.2024.1423786

Fetomaternal hemorrhage and its association with pronounced neonatal anemia: a case study report

Provisionally accepted
Peng Li Peng Li 1Hua Shu Hua Shu 2*Peng Lin Peng Lin 2Jishui Wang Jishui Wang 2*Di Zhang Di Zhang 2*Dongmei Man Dongmei Man 2*Fengge Wang Fengge Wang 1,2*
  • 1 Jining Medical University, Jining, China
  • 2 Affiliated Hospital of Jining Medical University, Jining, Shandong Province, China

The final, formatted version of the article will be published soon.

    Fetomaternal hemorrhage (FMH) is a perplexing obstetric condition that predominantly occurs during the third trimester or at the time of delivery. Its insidious and non-specific onset often leads to diagnostic challenges. The underlying pathophysiology of FMH remains incompletely understood, though it is primarily attributed to compromise of the placental barrier. The severity of the condition is intrinsically associated with the volumn of blood loss, the hemorrhage rate, and the presence of alloimmunity. Upon the occurrence of severe FMH, it can rapidly lead to intrauterine distress, fetal anemia, and the possibility of fetal demise, presenting a considerable threat to both maternal and neonatal well-being. In this article, I present a substantial case of FMH and conduct a systematic review of the current scientific literature regarding the etiology, clinical manifestations, diagnostic approaches, treatment highlights, and prognosis of this condition. The objective of this work is to improve clinicians' comprehension and diagnostic proficiency concerning FMH.

    Keywords: Fetomaternal hemorrhage, Severe neonatal anemia, Pregnancy, Obstetrics, case report

    Received: 24 Jun 2024; Accepted: 10 Sep 2024.

    Copyright: © 2024 Li, Shu, Lin, Wang, Zhang, Man and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Hua Shu, Affiliated Hospital of Jining Medical University, Jining, 272000, Shandong Province, China
    Jishui Wang, Affiliated Hospital of Jining Medical University, Jining, 272000, Shandong Province, China
    Di Zhang, Affiliated Hospital of Jining Medical University, Jining, 272000, Shandong Province, China
    Dongmei Man, Affiliated Hospital of Jining Medical University, Jining, 272000, Shandong Province, China
    Fengge Wang, Affiliated Hospital of Jining Medical University, Jining, 272000, Shandong Province, China

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