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ORIGINAL RESEARCH article

Front. Pediatr.
Sec. Pediatric Pulmonology
Volume 12 - 2024 | doi: 10.3389/fped.2024.1409687
This article is part of the Research Topic Pulmonary infection in children View all articles

Clinical Differences Between Mycoplasma pneumoniae Pneumonia and Streptococcus Pneumoniae Pneumonia : a case control study

Provisionally accepted
Jinping Ruan Jinping Ruan 1Linyan Ying Linyan Ying 2*Zhou Fu Zhou Fu 3
  • 1 Chongqing Red Cross Hospital, Jiangbei Qu, Chongqing, China
  • 2 Chongqing Medical University, Chongqing, China
  • 3 Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing, China

The final, formatted version of the article will be published soon.

    Mycoplasma pneumoniae pneumonia (MPP) and Streptococcus pneumoniae pneumonia (SPP) are common causes of respiratory tract infection, the study aimed to explore the differences in clinical features between children with MPP and those with SPP. 506 patients with MPP were compared to 311 patients with SPP in terms of clinical differences. The MPP group with a median age of 60 [29-89] months and the SPP group with a median age of 24 [10-40] months.Patients with MPP were older and had a higher occurrence of receiving antibiotics before admission, fever, dry cough, polypnea, and diarrhea than patients with SPP (all p<0.01).Patients with SPP were more likely to have wheezing, cyanosis and irritability (all p<0.01).Laboratory findings in our study showed that there were significant differences between MPP and SPP patients in mean leucocyte count, neutrophil % (N%), lymphocyte % (L%), ALT levels, AST levels, LDH levels, and incidence of accelerated procalcitonin (PCT) (all p<0.01). Lower age, no dry cough, no polypnea, lower LDH levels, and higher PCT might lead to the diagnosis of SPP. Our study showed that age had a higher accuracy in predicting MPP than LDH levels, with an age>48.5 months shown to be an independent predictive factor for the early evaluation and identification of MPP. In conclusion, patients with MPP and SPP usually present with fever, cough, and some nonspecific symptoms. Our study showed that age, dry cough, polypnea, LDH levels, and PCT levels were independent predictive factors associated with MPP and SPP.

    Keywords: Mycoplasma pneumoniae pneumonia, Streptococcus pneumoniae pneumonia, early diagnosis, independent predictive factor, Clinical differences

    Received: 30 Mar 2024; Accepted: 08 Jul 2024.

    Copyright: © 2024 Ruan, Ying and Fu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Linyan Ying, Chongqing Medical University, Chongqing, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.