AUTHOR=Destro Francesca , Durante Eleonora , Salerno Raffaele , Campari Alessandro , Meroni Milena , Diotto Veronica , Brunero Marco , Pelizzo Gloria 

TITLE=Case Report: Chronic pancreatitis in children as the cumulative effect of bilio-pancreatic abnormalities and genetic mutations

JOURNAL=Frontiers in Pediatrics

VOLUME=12

YEAR=2024

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2024.1393891

DOI=10.3389/fped.2024.1393891

ISSN=2296-2360

ABSTRACT=<p>Pancreatitis, in general, is a high-morbidity condition. Genetic conditions and anatomic variants are sometimes seen, especially in children, where biliary etiologies and alcohol are less common than in adults. The decision to intervene, the combined operative-endoscopic strategy, and the timing pose unique challenges. We report the case of a 10-year-old boy with PRSS1 mutation and pancreatic duct duplication, discussing the management and reviewing the recent reports in the Literature.</p>