AUTHOR=Surak Aimann , Sidhu Amneet , Ting Joseph Y. 

TITLE=Should we “eliminate” PDA shunt in preterm infants? A narrative review

JOURNAL=Frontiers in Pediatrics

VOLUME=12

YEAR=2024

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2024.1257694

DOI=10.3389/fped.2024.1257694

ISSN=2296-2360

ABSTRACT=<p>The patent ductus arteriosus frequently poses a significant morbidity in preterm infants, subjecting their immature pulmonary vascular bed to substantial volume overload. This, in turn, results in concurrent hypoperfusion to post-ductal organs, and subsequently alters cerebral blood flow. In addition, treatment has not demonstrated definitive improvements in patient outcomes. Currently, the optimal approach remains a subject of considerable debate with ongoing research controversy regarding the best approach. This article provides a comprehensive review of existing literature.</p>