AUTHOR=Wirayannawat Wariphan , Amawat Jutharat , Yamsiri Nattaya , Paes Bosco , Kitsommart Ratchada 

TITLE=Comparison of the SenSmart™ and the INVOS™ neonatal cerebral near-infrared spectrometry devices

JOURNAL=Frontiers in Pediatrics

VOLUME=11

YEAR=2023

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2023.1243977

DOI=10.3389/fped.2023.1243977

ISSN=2296-2360

ABSTRACT=<sec><title>Objectives</title><p>To determine the correlation and agreement between the SenSmart™ and the INVOS™ devices of neonatal cerebral regional oxygen saturation (CrSO<sub>2</sub>) measurements using neonatal sensors. The secondary objective was to develop a regression model that predicts CrSO<sub>2</sub>-INVOS values using CrSO<sub>2</sub>-SenSmart indices and determine whether the values between the devices are interchangeable.</p></sec><sec><title>Methods</title><p>A prospective, cross-sectional study was conducted in infants during the first 4 weeks of life. Simultaneous, bilateral CrSO<sub>2</sub> was measured using the SenSmart™X100 (CrSO<sub>2</sub>-SenSmart) or INVOS™ 5100C (CrSO<sub>2</sub>-INVOS) device in each frontoparietal area for 2 h. Five-minute CrSO<sub>2</sub> values were extracted for analysis.</p></sec><sec><title>Results</title><p>Thirty infants were recruited with 720 pairwise measurements and 26 (84%) were evaluated in the first week of life. Mean gestational age of the preterm and term infants was [30.9 ± 2.8 (<italic>n</italic> = 14) and 38.8 ± 1.1 (<italic>n</italic> = 16)] weeks, respectively. Overall CrSO<sub>2</sub>- was 77.08 ± 9.70% and 71.45 ± 12.74% for the SenSmart and INVOS, respectively (<italic>p</italic> &lt; 0.001). The correlation coefficient (<italic>r</italic>) between the CrSO<sub>2</sub>-SenSmart and INVOS was 0.20 (<italic>p</italic> &lt; 0.001). The mean difference between the CrSO<sub>2</sub>-SenSmart and INVOS was 5.63 ± 13.87% with −21.6% to 32.8% limits of agreement. The <italic>r</italic> and mean difference was 0.39 (<italic>p</italic> &lt; 0.001) and 8.87 ± 12.58% in preterm infants, and 0.06 (<italic>p</italic> = 0.27) and 2.79 ± 14.34 in term infants.</p></sec><sec><title>Conclusion</title><p>The CrSO<sub>2</sub>-SenSmart tended to read higher than the CrSO<sub>2</sub>-INVOS device. There was no correlation between the CrSO<sub>2</sub>-SenSmart and the CrSO<sub>2</sub>-INVOS in term infants and it was weak in preterms. Due to imprecise agreement, the CrSO<sub>2</sub>-SenSmart values are not interchangeable with those of the CrSO<sub>2</sub>-INVOS.</p></sec>