AUTHOR=Panebianco Mario , Limonjiani Eduard , Formigari Roberto , Bordonaro Veronica , Secinaro Aurelio , Cetrano Enrico , Carotti Adriano , Galletti Lorenzo , Albanese Sonia 

TITLE=Case report: Epstein–Barr virus and constrictive pericarditis—An unusual combination

JOURNAL=Frontiers in Pediatrics

VOLUME=11

YEAR=2023

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2023.1215928

DOI=10.3389/fped.2023.1215928

ISSN=2296-2360

ABSTRACT=<p>Constrictive pericarditis is a chronic inflammatory process that can lead to heart failure if not diagnosed and treated correctly. Although Epstein–Barr virus (EBV)–related pericarditis is a very rare condition, it should still be considered for a differential diagnosis. We report the case of an 18-year-old male, who was surgically treated for constrictive pericarditis, in which <italic>in situ</italic> hybridization to Epstein–Barr virus-encoded RNA (EBER) probe of the excised pericardium led to the subsequent etiological diagnosis of chronic pericarditis caused by EBV.</p>