AUTHOR=He Yan , Wu Xuemin , Xu Yingrui , Liu Zhaoquan , Du Guoqiang , Wu Xiangyu , Liu Wei , Wu Rongde 

TITLE=Ureteral dilation recovery after intravesical reimplantation in children with primary obstructive megaureter

JOURNAL=Frontiers in Pediatrics

VOLUME=11

YEAR=2023

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2023.1164474

DOI=10.3389/fped.2023.1164474

ISSN=2296-2360

ABSTRACT=<sec><title>Background</title><p>To observe the postoperative recovery following ureteral dilation in primary obstructive megaureter (POM) after ureteral implantation, and evaluate the risk factors affecting ureter diameter resolution.</p></sec><sec><title>Materials and Methods</title><p>A retrospective study was performed in patients with POM who underwent ureteral reimplantation using the Cohen procedure. Patient characteristics, perioperative parameters, and postoperative outcomes were also analysed. A widest ureteral diameter of &lt;7 mm was defined as a normal shape and outcome. Survival time was defined as the time from surgery to ureteral dilation recovery or to the last follow-up.</p></sec><sec><title>Results</title><p>A total of 49 patients (54 ureters) were included in the analysis. The survival time ranged from 1 to 53 months. The shapes of a total of 47 (87.04%) megaureters recovered, and most (29/47) resolutions happened within 6 months after surgery. In the univariate analysis, bilateral ureterovesical reimplantation (<italic>p </italic>= 0.015), ureteral terminal tapering (<italic>p </italic>= 0.019), weight (<italic>p </italic>= 0.036), and age (<italic>p </italic>= 0.015) were associated with the recovery time of ureteral dilation. A delayed recovery of ureteral diameter was noted in bilateral reimplantation (HR = 0.336, <italic>p </italic>= 0.017) using multivariate Cox regression.</p></sec><sec><title>Conclusions</title><p>Ureteral dilation in POM mostly returned to normal within six postoperative months. Moreover, bilateral ureterovesical reimplantation is a risk factor for delayed postoperative recovery of ureter dilation in POM.</p></sec>