AUTHOR=Mauro Angela , Casini Francesca , Talenti Antonella , Di Mari Clelia , Benincaso Anna Rita , Di Nardo Giovanni , Bernardo Luca 

TITLE=Celiac crisis as the life-threatening onset of celiac disease in children: a case report

JOURNAL=Frontiers in Pediatrics

VOLUME=11

YEAR=2023

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2023.1163765

DOI=10.3389/fped.2023.1163765

ISSN=2296-2360

ABSTRACT=<p>Celiac disease (CD) is an immune-mediated enteropathy caused by a permanent sensitivity to gluten in genetically susceptible individuals. In rare cases, CD may occur with a severe potential life-threatening manifestation known as a celiac crisis (CC). This may be a consequence of a delayed diagnosis and expose patients to possible fatal complications. We report the case of a 22-month-old child admitted to our hospital for a CC characterized by weight loss, vomiting, and diarrhea associated with a malnutrition state. Early identification of symptoms of CC is essential to provide a prompt diagnosis and management.</p>