AUTHOR=Zheng Bo , Fu Jianhua 

TITLE=Telomere dysfunction in some pediatric congenital and growth-related diseases

JOURNAL=Frontiers in Pediatrics

VOLUME=11

YEAR=2023

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2023.1133102

DOI=10.3389/fped.2023.1133102

ISSN=2296-2360

ABSTRACT=<p>Telomere wear and dysfunction may lead to aging-related diseases. Moreover, increasing evidence show that the occurrence, development, and prognosis of some pediatric diseases are also related to telomere dysfunction. In this review, we systematically analyzed the relationship between telomere biology and some pediatric congenital and growth-related diseases and proposed new theoretical basis and therapeutic targets for the treatment of these diseases.</p>