AUTHOR=Lloyd Audrey R. , Ardura Monica I. , Wise Kelly , Chavarin Daniel J. , Boyle Brendan , Sivaraman Vidya 

TITLE=Barriers to vaccination in immunocompromised children: A needs assessment in children with childhood-onset SLE and inflammatory bowel disease

JOURNAL=Frontiers in Pediatrics

VOLUME=11

YEAR=2023

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2023.1103096

DOI=10.3389/fped.2023.1103096

ISSN=2296-2360

ABSTRACT=<sec><title>Background</title><p>Vaccination of immunocompromised children (ICC) remains suboptimal.</p></sec><sec><title>Methods</title><p>Needs assessment surveys were administered to patients and caregivers during routine ambulatory visits to the rheumatology and gastroenterology clinics at Nationwide Children's Hospital (NCH) from January 1 through August 31, 2018, and to community primary care physicians (PCPs) at their monthly meeting and electronically.</p></sec><sec><title>Results</title><p>Completed surveys were received for 57 patients <bold>(</bold>31 with childhood-onset systemic lupus erythematosus (c-SLE) and 26 with inflammatory bowel disease (IBD)) and 30 PCPs. Of the patient cohort, 93% (<italic>n</italic> = 53) felt their PCP was well informed about vaccines and 84% (<italic>n</italic> = 47) received vaccinations from either their PCP or local health department. Two patient surveys noted concerns of vaccine safety. Among the 30 responses completed by PCPs 50% (<italic>n</italic> = 15) preferred to provide all vaccines themselves, however, only 40% (<italic>n</italic> = 12) of PCPs felt “very confident” when providing vaccines to ICC. Further, 83% (<italic>n</italic> = 25) did not stock the 23-valent pneumococcal vaccine and only 27% (<italic>n</italic> = 8) routinely recommended vaccination of household contacts.</p></sec><sec><title>Conclusions</title><p>Our study found a discordance between parent and PCP comfort in vaccinating ICC, highlighting an important barrier to vaccination in this patient population. In our cohort of patients, vaccine hesitancy was not a barrier to vaccination.</p></sec>