AUTHOR=Nusman Charlotte M. , Schalij-Delfos Nicoline E. , Groenwold Rolf H. H. , Onland Wes 

TITLE=Considerations for future studies on the effect of late phase oxygen strategies on retinopathy of prematurity

JOURNAL=Frontiers in Pediatrics

VOLUME=10

YEAR=2022

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2022.975613

DOI=10.3389/fped.2022.975613

ISSN=2296-2360

ABSTRACT=<p>Strategies to ensure high intraocular oxygen delivery to the developing retina after 32 weeks gestational age, such as higher saturation targets and/or higher hemoglobin levels, are hypothesized to prevent ophthalmological treatment for retinopathy of prematurity (ROP). This short report summarizes the current evidence of these strategies, and discusses possibilities of future studies. A large sample size would be required and therefore the feasibility of a future randomized controlled trial is questioned.</p>