AUTHOR=Cubík Jakub , Kepak Stanislav , Wiedermannova Hana , Vrtkova Adela , Burckova Hana , Zarubova Pavla , Fernandez Carlos , Pavlicek Jan , Jargus Jan , Vasinek Vladimir 

TITLE=Measuring respiratory and heart rate using a fiber optic interferometer: A pilot study in a neonate model

JOURNAL=Frontiers in Pediatrics

VOLUME=10

YEAR=2022

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2022.957835

DOI=10.3389/fped.2022.957835

ISSN=2296-2360

ABSTRACT=<sec><title>Introduction</title><p>The study aim was to test the safety and efficacy of a pad with optic fibers developed for monitoring newborn respiratory rate (RR) and heart rate (HR).</p></sec><sec><title>Methods</title><p>Thirty New Zealand White rabbits were included, divided by weight into three groups. RR and HR were measured using two methods for each rabbit: ECG electrodes as the reference method and a newly developed pad with an experimental fiber optic system (EFOS) as the experimental method.</p></sec><sec><title>Results</title><p>Analysis was performed on data for 29 rabbits (10 female, 34%; 19 male, 66%). EFOS performed better at measuring RR compared with HR. RR values did not differ significantly between the methods for the whole group (<italic>p</italic> = 0.151) or within each sex (female: <italic>p</italic> &gt; 0.999; male: <italic>p</italic> = 0.075). Values for HR, however, did differ between methods for the whole group of animals (<italic>p</italic> &lt; 0.001) and also within groups by sex (female: <italic>p</italic> &lt; 0.001; male: <italic>p</italic> = 0.006).</p></sec><sec><title>Conclusion</title><p>The results of this preclinical study demonstrate the potential of this non-invasive method using a fiber optic pad to measure HR and RR.</p></sec>