AUTHOR=Dramowski Angela , Aucamp Marina , Beales Emily , Bekker Adrie , Cotton Mark Frederic , Fitzgerald Felicity C. , Labi Appiah-Korang , Russell Neal , Strysko Jonathan , Whitelaw Andrew , Coffin Susan TITLE=Healthcare-Associated Infection Prevention Interventions for Neonates in Resource-Limited Settings JOURNAL=Frontiers in Pediatrics VOLUME=10 YEAR=2022 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2022.919403 DOI=10.3389/fped.2022.919403 ISSN=2296-2360 ABSTRACT=

Healthcare-associated infections (HAIs) and antimicrobial-resistant (AMR) infections are leading causes of neonatal morbidity and mortality, contributing to an extended hospital stay and increased healthcare costs. Although the burden and impact of HAI/AMR in resource-limited neonatal units are substantial, there are few HAI/AMR prevention studies in these settings. We reviewed the mechanism of action and evidence supporting HAI/AMR prevention interventions, including care bundles, for hospitalized neonates in low- and middle-income countries (LMIC).