AUTHOR=van der Velden Fabian J. S. , van Delft Frederik , Owens Stephen , Llevadias Judit , McKean Michael , Pulford Lindsey , Taha Yusri , Williamson Grace , Campbell-Hewson Quentin , Hambleton Sophie , Payne Rebecca , Duncan Christopher , Johnston Catriona , Spegarova Jarmila , Emonts Marieke TITLE=Case Report: Severe Acute Pulmonary COVID-19 in a Teenager Post Autologous Hematopoietic Stem Cell Transplant JOURNAL=Frontiers in Pediatrics VOLUME=10 YEAR=2022 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2022.809061 DOI=10.3389/fped.2022.809061 ISSN=2296-2360 ABSTRACT=

Pulmonary severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children is generally described as mild, and SARS-CoV-2 infection in immunocompromised children are observed as generally mild as well. A small proportion of pediatric patients will become critically ill due to (cardio)respiratory failure and require intensive care treatment. We report the case of a teenager with Hodgkin's lymphoma who acquired SARS-CoV-2 (detected by PCR) on the day of her autologous stem cell transplant and developed acute respiratory distress syndrome, successfully treated with a combination of antivirals, immunomodulation with steroids and biologicals, and ECMO.