AUTHOR=van der Hout-van der Jagt M. Beatrijs , Verweij E. J. T. , Andriessen Peter , de Boode Willem P. , Bos Arend F. , Delbressine Frank L. M. , Eggink Alex J. , Erwich Jan Jaap H. M. , Feijs Loe M. G. , Groenendaal Floris , Kramer Boris W. W. , Lely A. Titia , Loop Rachel F. A. M. , Neukamp Franziska , Onland Wes , Oudijk Martijn A. , te Pas Arjan B. , Reiss Irwin K. M. , Schoberer Mark , Scholten Ralph R. , Spaanderman Marc E. A. , van der Ven Myrthe , Vermeulen Marijn J. , van de Vosse Frans N. , Oei S. Guid TITLE=Interprofessional Consensus Regarding Design Requirements for Liquid-Based Perinatal Life Support (PLS) Technology JOURNAL=Frontiers in Pediatrics VOLUME=9 YEAR=2022 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2021.793531 DOI=10.3389/fped.2021.793531 ISSN=2296-2360 ABSTRACT=

Liquid-based perinatal life support (PLS) technology will probably be applied in a first-in-human study within the next decade. Research and development of PLS technology should not only address technical issues, but also consider socio-ethical and legal aspects, its application area, and the corresponding design implications. This paper represents the consensus opinion of a group of healthcare professionals, designers, ethicists, researchers and patient representatives, who have expertise in tertiary obstetric and neonatal care, bio-ethics, experimental perinatal animal models for physiologic research, biomedical modeling, monitoring, and design. The aim of this paper is to provide a framework for research and development of PLS technology. These requirements are considering the possible respective user perspectives, with the aim to co-create a PLS system that facilitates physiological growth and development for extremely preterm born infants.