AUTHOR=Fischer Hendrik S. , Reibel Nora J. , Bührer Christoph , Dame Christof TITLE=Prophylactic Erythropoietin for Neuroprotection in Very Preterm Infants: A Meta-Analysis Update JOURNAL=Frontiers in Pediatrics VOLUME=9 YEAR=2021 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2021.657228 DOI=10.3389/fped.2021.657228 ISSN=2296-2360 ABSTRACT=

A meta-analysis update of randomized controlled trials investigating recombinant human erythropoietin suggests improved neurodevelopmental outcome in preterm infants. There was substantial heterogeneity, which could be ascribed to a single trial. Exclusion of this trial featuring a high risk of bias abolished heterogeneity and any effects of recombinant human erythropoietin treatment.