AUTHOR=Kahn Stacie , Chegondi Madhuradhar , Nellis Marianne E. , Karam Oliver 

TITLE=Overview of Plasma and Platelet Transfusions in Critically Ill Children

JOURNAL=Frontiers in Pediatrics

VOLUME=8

YEAR=2020

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2020.601659

DOI=10.3389/fped.2020.601659

ISSN=2296-2360

ABSTRACT=<p>Critically ill children are a unique population who frequently receive plasma and platelet transfusions for both active bleeding and mitigation of bleeding risk. While these products are frequently administered, transfusion indications in this population remain unclear, and practice varies across institutions and providers. In this manuscript, we will outline the current evidence regarding plasma and platelet transfusions for hemostasis in the pediatric intensive care setting. For both products, we will describe the product composition, epidemiology, and product indications and discuss the potential risks and benefits involved with the transfusion. We will also discuss knowledge gaps and future areas of research.</p>