AUTHOR=Lee Tsung-Han , Juan I-Cheng , Hsu Hsiu-Ying , Chen Wen-Liang , Huang Cheng-Chieh , Yang Mei-Chueh , Lei Wei-Yuan , Lin Chih-Ming , Chou Chu-Chung , Chang Chin-Fu , Lin Yan-Ren 

TITLE=Demographics of Pediatric OHCA Survivors With Postdischarge Diseases: A National Population-Based Follow-Up Study

JOURNAL=Frontiers in Pediatrics

VOLUME=7

YEAR=2020

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2019.00537

DOI=10.3389/fped.2019.00537

ISSN=2296-2360

ABSTRACT=<p><bold>Background:</bold> Postdischarge diseases (PDDs) have been reported for adult survivors of out-of-hospital cardiac arrest (OHCA). However, the detailed demographics of pediatric OHCA survivors with PDDs are not well-documented, and information regarding functional survivors is particularly limited. We aimed to report detailed information on the PDDs of survivors of traumatic and non-traumatic pediatric OHCA using a national healthcare database.</p><p><bold>Methods:</bold> We retrospectively obtained data from the Taiwan government healthcare database (2011–2015). Information on the demographics of traumatic and non-traumatic pediatric OHCA survivors (&lt;20 years) was obtained and reported. The patients who survived to discharge (survivors) and those classified as functional survivors were followed up for 1 year for the analysis of newly diagnosed PDDs. The time from discharge to PDD diagnosis was also reported.</p><p><bold>Results:</bold> A total of 2,178 non-traumatic and 288 traumatic OHCA pediatric cases were included. Among the non-traumatic OHCA survivors (<italic>n</italic> = 374, survival rate = 17.2%), respiratory tract (<italic>n</italic> = 270, 72.2%), gastrointestinal (<italic>n</italic> = 187, 50.0%), and neurological diseases (<italic>n</italic> = 167, 49.1%) were the three most common PDD categories, and in these three categories, the majority of PDDs were atypical/influenza pneumonia, non-infective acute gastroenteritis, and generalized/status epilepsy, respectively. Among the traumatic OHCA survivors (<italic>n</italic> = 21, survival rate = 7.3%), respiratory tract diseases (<italic>n</italic> = 17, 81.0%) were the most common, followed by skin or soft tissue (<italic>n</italic> = 14, 66.7%) diseases. Most functional survivors still suffered from neurological and respiratory tract diseases. Most PDDs, except for skin or soft tissue diseases, were newly diagnosed within the first 3 months after discharge.</p><p><bold>Conclusions:</bold> Respiratory tract (pneumonia), neurological (epilepsy), and skin or soft tissue (dermatitis) diseases were very common among both non-traumatic and traumatic OHCA survivors. More importantly, most PDDs, except for skin or soft tissue diseases, were newly diagnosed within the first 3 months after discharge.</p>