AUTHOR=Haddad Elie , Hoenig Manfred 

TITLE=Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)

JOURNAL=Frontiers in Pediatrics

VOLUME=7

YEAR=2019

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2019.00481

DOI=10.3389/fped.2019.00481

ISSN=2296-2360

ABSTRACT=<p>Severe Combined Immunodeficiencies (SCID) are a heterogeneous group of monogenetic diseases. We describe the typical clinical presentation of patients with SCID as well as basic principles in diagnosis and therapy by hematopoietic stem cell transplantation. Therapeutic strategies may differ between subtypes and the inherent reduced capacity or inablility to reject a graft have to be considered.</p>