AUTHOR=Khalila Aya , Shavit Itai , Shaoul Ron 

TITLE=Propofol Sedation by Pediatric Gastroenterologists for Endoscopic Procedures: A Retrospective Analysis

JOURNAL=Frontiers in Pediatrics

VOLUME=7

YEAR=2019

URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2019.00098

DOI=10.3389/fped.2019.00098

ISSN=2296-2360

ABSTRACT=<p><bold>Background:</bold> There is a substantial literature on the favorable outcome of propofol administration by non-anesthesiologists for endoscopy in adults; however, very few data are currently available on propofol sedation by pediatric gastroenterologists. Aims: to evaluate the safety of propofol sedation by pediatric gastroenterologists.</p><p><bold>Methods:</bold> A retrospective chart review of all children who were sedated by pediatric gastroenterologists in three Northern Israeli hospitals over a 4 years period Demographic and medical characteristics and any data regarding the procedure were extracted from patient's records. The main outcome measurements were procedure completion and reported adverse events.</p><p><bold>Results:</bold> Overall, 1,214 endoscopic procedures for were performed during this period. Complete data was available for 1,190 procedures. All children sedated by pediatric gastroenterologists were classified as ASA I or II. Propofol dosage (in mg/kg) inversely correlated with patient age. The younger the child the higher the dose needed to reach a satisfactory level of sedation (<italic>r</italic> = −0.397, <italic>p</italic> &lt; 0.001). The addition of fentanyl significantly decreased propofol dosage needed to provide optimal sedation, <italic>p</italic> &lt; 0.001. Nine (0.7%) reversible adverse events were reported. All the procedures were successfully completed and all patients were discharged home.</p><p><bold>Conclusions:</bold> We conclude that our approach is safe in children as it is in adults and can be implemented for children with ASA I, II.</p>