CLINICAL TRIAL article

Front. Pain Res.

Sec. Neuromodulatory Interventions

Volume 6 - 2025 | doi: 10.3389/fpain.2025.1525964

This article is part of the Research TopicNon-invasive Therapy for Pain ReliefView all articles

Effects on Perceived Pain and Somatosensory Function After Transcutaneous Neuromodulation in Patients with Chronic Low Back Pain: A Quasi-Experimental Study with a Crossover Intervention

Provisionally accepted
  • 1University of Valencia, Valencia, Valencian Community, Spain
  • 2European University of Madrid, Villaviciosa de Odón, Spain
  • 3University of Alcalá, Alcalá de Henares, Madrid, Spain
  • 4Universidad de Flores, Buenos Aires, Buenos Aires, Argentina
  • 5Florida Gulf Coast University, Fort Myers, Florida, United States

The final, formatted version of the article will be published soon.

Transcutaneous magnetic neuromodulation is a noninvasive technique that may influence pain perception and mobility by modulating epidermal afferents and autonomic nervous system activity. However, its effects on chronic non-specific low back pain (CNSLBP) remain unclear.This study evaluated the effects of transcutaneous neuromodulation applied to the lumbar spine on the pressure pain threshold (PPT) and ankle dorsiflexion range of motion (DROM) in patients with chronic non-specific low back pain (CNSLBP).A single-group prospective cohort study with crossover intervention was conducted between March 2022 and September 2022. A convenience sample of 39 patients with CNSLBP was included in this study. Each participant received two interventions in a randomized sequence: transcutaneous neuromodulation with magnetic tape particles (TMP) and placebo kinesiology tape (KT). A one-week washout period was implemented Information Classification: General (0.54, 0.735)]. Pairwise leg comparisons were not significant (p>0.05). For the pressure pain threshold, significant differences (p<0.05) with moderate to large effect sizes were observed. PPTs varied by vertebral level, with significant differences in site-specific comparisons between specific levels.Conclusions: Transcutaneous neuromodulation using magnetic tape applied to the lumbar spine reduces perceived pain and increases ankle dorsiflexion range of motion in patients with CNSLBP. These findings suggest that epidermal afferent modulation may contribute to pain relief and motor function enhancement, providing a novel approach for noninvasive pain management.

Keywords: somatosensory, Chronic low back pain, transcutaneous, Epidermis, neuromodulation (5-7 keywords)

Received: 11 Nov 2024; Accepted: 25 Mar 2025.

Copyright: © 2025 Selva-Sarzo, Sánchez Romero, Cuenca Zaldivar, García-Haba, Akiyama, Sillevis and Fernández-Carnero. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Eleuterio A. Sánchez Romero, European University of Madrid, Villaviciosa de Odón, Spain

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