
94% of researchers rate our articles as excellent or good
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.
Find out more
CLINICAL TRIAL article
Front. Pain Res.
Sec. Neuromodulatory Interventions
Volume 6 - 2025 | doi: 10.3389/fpain.2025.1525964
This article is part of the Research TopicNon-invasive Therapy for Pain ReliefView all articles
The final, formatted version of the article will be published soon.
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Transcutaneous magnetic neuromodulation is a noninvasive technique that may influence pain perception and mobility by modulating epidermal afferents and autonomic nervous system activity. However, its effects on chronic non-specific low back pain (CNSLBP) remain unclear.This study evaluated the effects of transcutaneous neuromodulation applied to the lumbar spine on the pressure pain threshold (PPT) and ankle dorsiflexion range of motion (DROM) in patients with chronic non-specific low back pain (CNSLBP).A single-group prospective cohort study with crossover intervention was conducted between March 2022 and September 2022. A convenience sample of 39 patients with CNSLBP was included in this study. Each participant received two interventions in a randomized sequence: transcutaneous neuromodulation with magnetic tape particles (TMP) and placebo kinesiology tape (KT). A one-week washout period was implemented Information Classification: General (0.54, 0.735)]. Pairwise leg comparisons were not significant (p>0.05). For the pressure pain threshold, significant differences (p<0.05) with moderate to large effect sizes were observed. PPTs varied by vertebral level, with significant differences in site-specific comparisons between specific levels.Conclusions: Transcutaneous neuromodulation using magnetic tape applied to the lumbar spine reduces perceived pain and increases ankle dorsiflexion range of motion in patients with CNSLBP. These findings suggest that epidermal afferent modulation may contribute to pain relief and motor function enhancement, providing a novel approach for noninvasive pain management.
Keywords: somatosensory, Chronic low back pain, transcutaneous, Epidermis, neuromodulation (5-7 keywords)
Received: 11 Nov 2024; Accepted: 25 Mar 2025.
Copyright: © 2025 Selva-Sarzo, Sánchez Romero, Cuenca Zaldivar, García-Haba, Akiyama, Sillevis and Fernández-Carnero. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Eleuterio A. Sánchez Romero, European University of Madrid, Villaviciosa de Odón, Spain
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Supplementary Material
Research integrity at Frontiers
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.