AUTHOR=Ren Ke TITLE=Grand Challenges in Musculoskeletal Pain Research: Chronicity, Comorbidity, Immune Regulation, Sex Differences, Diagnosis, and Treatment Opportunities JOURNAL=Frontiers in Pain Research VOLUME=1 YEAR=2020 URL=https://www.frontiersin.org/journals/pain-research/articles/10.3389/fpain.2020.575479 DOI=10.3389/fpain.2020.575479 ISSN=2673-561X