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REVIEW article

Front. Oral. Health
Sec. Preventive Dentistry
Volume 5 - 2024 | doi: 10.3389/froh.2024.1412751

Physicochemical Properties, Biological Chemistry and Mechanisms of Action of Caries-Arresting Diammine-Silver(I) Fluoride and Silver(I)-Fluoride Solutions for Clinical Use: A Critical Review †

Provisionally accepted
Kayleigh Hunwin Kayleigh Hunwin 1Georgina Page Georgina Page 1Mark Edgar Mark Edgar 1Adolfo Botana Adolfo Botana 2Rachel Armitage Rachel Armitage 1Mohammed Bhogadia Mohammed Bhogadia 1Unmesh Desai Unmesh Desai 1Steven Duffin Steven Duffin 3Marcus Duffin Marcus Duffin 3Wyman Chan Wyman Chan 4Martin Grootveld Martin Grootveld 1*
  • 1 De Montfort University, Leicester, United Kingdom
  • 2 Jeol (United Kingdom), Welwyn Garden City, England, United Kingdom
  • 3 NoDK LLC/Oral Health Outreach LLC, 25195 SW Parkway Ave Ste 206 Wilsonville, OR 97070 USA, Wilsonville, Oregon, United States
  • 4 SmileStudio (UK) Ltd., 1st Floor Wingate House, 93-107 Shaftesbury Avenue, London W1D 8BT, UK, London, United Kingdom

The final, formatted version of the article will be published soon.

    † This critical review represents an accompanying Part II paper to the full research paper entitled 'Explorations of the chemical constitution and aqueous solution status of caries-arresting silver(I)diammine fluoride and silver(I)-fluoride products using high-resolution 19 F NMR analysis. Spectroscopic and SEM investigations of their interactions with human saliva: Evidence for the in vivo salivary-catalysed autoconstruction of Ag/AgCl-based nanoparticles (IV-SCAN) -Part I.' by K. Hunwin et al. Front Oral Health. In press (2024).

    Keywords: Dental Caries, Human saliva, Diammine-Silver(I) Fluoride (SDF), Silver(I)-Fluoride (SF), Silver(I)-Chloride (AgCl), Chromophoric Ag/AgCl-Based Nanoparticles (CSNPs), IV-SCAN, Mechanisms of Action (MoAs)

    Received: 05 Apr 2024; Accepted: 28 Jun 2024.

    Copyright: © 2024 Hunwin, Page, Edgar, Botana, Armitage, Bhogadia, Desai, Duffin, Duffin, Chan and Grootveld. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Martin Grootveld, De Montfort University, Leicester, United Kingdom

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.