94% of researchers rate our articles as excellent or good
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.
Find out more
ORIGINAL RESEARCH article
Front. Ophthalmol.
Sec. Cornea and Refractive Surgery
Volume 5 - 2025 | doi: 10.3389/fopht.2025.1562555
This article is part of the Research Topic New Concepts, Advances, and Future Trends in Clinical Research on Eye Diseases View all 23 articles
Femtosecond laser-assisted in situ keratomileusis for the correction of residual ametropia after penetrating keratoplasty: 1-year follow-up
Provisionally accepted
Dario Pasquale Mucciolo 1*
Giancarlo Albani 1 Luca Terracciano 2 Marco Branchetti 1 Laura Luchetti 1 Vittoria Murro 1
Gianni Virgili 1
Fabrizio Giansanti 1- 1 University of Florence, Florence, Italy
- 2 SOC Oculistica Prato, Azienda USL Toscana Centro, Florence, Italy
Background: After an optimal corneal transplantation, a residual refractive error is possible due to several factors. We evaluated the 1-yr follow up of laser-assisted in situ keratomileusis using femtosecond laser (LASIK) for the correction of residual ametropia after penetrating keratoplasty (PK).Methods: Ten eyes of 10 patients were treated using corneal Femto-LASIK (F-LASIK) (WaveLight Ⓡ Refractive Suite, Alcon) to correct refractive errors after PK at Careggi Teaching Hospital (Florence, Italy). The main outcomes included uncorrected and corrected distance visual acuity (UDVA, CDVA), preoperative and postoperative manifest refraction, and corneal topography. All patients were evaluated the day after surgery and 1, 4, 12, 24, 48 weeks later.Results: At the 48-week follow up, all patients showed a significant improvement in their UDVA (mean: 0.70 ± 0.29 LogMAR vs 0.50 ± 0.22 LogMAR, p<0.05) as well as in the spherical equivalent value (SE) (mean: -4,51±2,36 vs. -1,55±0.77, p=0.001), the cylindrical ametropia (mean: -6.13±2.04 vs. -3.2±2.15, p<0.05) and the CDVA improved although not statistically significant (0.32± 0.24 vs 0.23±0.13 LogMAR, p>0.05). These values were observed from the 12-week follow up onwards. Post-operative spherical ametropia was not statistically significant. Intraoperative and postoperative complications were not detected.Conclusions: UDVA significantly improved using Femto-LASIK without surgical complications. The refractive results were stable from the 3-mth to the 1-yr follow ups. Femto-LASIK is an effective and safe choice to treat post-PK refractive errors.
Keywords: femtolaser LASIK, Penetrating keratoplasty, PKP, post-operative ametropia, Refractive surgery
Received: 17 Jan 2025; Accepted: 28 Feb 2025.
Copyright: © 2025 Mucciolo, Albani, Terracciano, Branchetti, Luchetti, Murro, Virgili and Giansanti. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Dario Pasquale Mucciolo, University of Florence, Florence, Italy
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.