Lower Adenoma Detection Rate in Anesthesia Assisted Colonoscopy: A Retrospective Study

Chang, Cai; XU, Zhihua; Ye, Bin

doi:10.3389/fonc.2025.1571387

CLINICAL TRIAL article

Front. Oncol.

Sec. Gastrointestinal Cancers: Colorectal Cancer

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1571387

This article is part of the Research Topic Advances in Medical Imaging for Precision Diagnostic and Therapeutic Applications in Digestive Diseases View all 5 articles

Lower Adenoma Detection Rate in Anesthesia Assisted Colonoscopy: A Retrospective Study

Provisionally accepted

Cai Chang

Zhihua XU

Bin Ye ^*

Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, China

The final, formatted version of the article will be published soon.

Objectives: As anesthesia assisted (AA) colonoscopy becomes increasingly popular, there has been concern about its impact on the quality of colonoscopy examinations. We aimed to clarify the impact of anesthesia assistance on the adenoma detection rate (ADR) and non-adenomatous polyp detection rate (PDR) of colonoscopy.We collected data from patients undergoing colonoscopy throughout the year 2023 at our institution, with a total of 16,465 cases identified for potential analysis. After using propensity score matching (PSM) to minimize the influence of other variables on the study outcomes, there were 6,094 cases remaining for analysis in both the AA group and non-AA group, respectively. Then, we compared the ADR and PDR between the two groups and analyzed the colon location and size of adenomas or polyps found in different groups.The ADR in the non-AA group (36.94%) was significantly higher than that in the AA group (26.40%) (p<0.0001), while there was no statistically significant difference in the PDR between the two groups. AA could also affect the probability of discovering adenomas or polyps in some colon segments, but had no significant effect on the size of the discovered adenomas or polyps. In addition, there were more significant advantages of ADR in the non-AA group among the more experienced endoscopists' cohort.Conclusions: Non-AA colonoscopy had a higher ADR, suggesting that while AA may potentially reduce patient stress responses to some extent, it confers few benefits in terms of adenoma detection.

Keywords: Lower Adenoma Detection Rate in Anesthesia Assisted Colonoscopy: A Retrospective Study colonoscopy, Endoscopy, Anesthesia assistance, ADR, PDR

Received: 05 Feb 2025; Accepted: 25 Mar 2025.

Copyright: © 2025 Chang, XU and Ye. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Bin Ye, Fifth Affiliated Hospital of Wenzhou Medical University, Lishui, China

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