CASE REPORT article

Front. Oncol.

Sec. Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1548570

This article is part of the Research TopicNovel Approaches in the Management of Hepatobiliary Pancreatic CancerView all 7 articles

A case report of a rare intrahepatic cholangiocarcinoma with rectal metastasis

Provisionally accepted
Shumin  JiangShumin JiangLu  HuangLu HuangQuan  JiangQuan Jiang*
  • Jinan University, Guangzhou, China

The final, formatted version of the article will be published soon.

Intrahepatic cholangiocarcinoma (ICC) is a primary liver cancer with insidious onset, rapid progression, and poor prognosis. Lymphatic system is the main route of ICC distant metastasis, with lungs, adrenal glands and brain as the most common extrahepatic sites. However, extrahepatic metastases of ICC have rarely been reported in patients with rectal symptoms as initial symptoms, and the diagnosis relies on the specific immunohistochemical features of intestinal lesion biopsy. Herein, this study presents an incidental case of ICC with rectal metastasis to investigate its characteristics based on its diagnosis, metastasis and treatment.

Keywords: intrahepatic cholangiocarcinoma, Rectal metastasis, Cancer treatment;, Tumor marker, Pathological features

Received: 19 Dec 2024; Accepted: 16 Apr 2025.

Copyright: © 2025 Jiang, Huang and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Quan Jiang, Jinan University, Guangzhou, China

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Research integrity at Frontiers

94% of researchers rate our articles as excellent or good

Learn more about the work of our research integrity team to safeguard the quality of each article we publish.


Find out more