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ORIGINAL RESEARCH article
Front. Oncol.
Sec. Head and Neck Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1537905
Clinical Characteristics and Recurrence Predictors of Sinonasal Inverted Papilloma: A Retrospective Cohort Study
Provisionally accepted- First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
Objective: To investigate the clinical characteristics and predictors of postoperative recurrence in sinonasal inverted papilloma (SNIP).Methods:A retrospective cohort study of 53 SNIP patients treated at Zhengzhou University Hospital (2019–2023) was conducted. Patients were stratified into primary (n=34) and recurrent (n=19) cohorts. Clinical variables were analyzed using univariate and multivariate logistic regression.Results: Smoking (OR=10.08, 95% CI=1.32–77.15), prior surgery (OR=17.26, 95% CI=2.69–110.76), and ipsilateral involvement (OR=7.79, 95% CI=1.05–57.99) emerged as independent recurrence predictors (P<0.05). Krouse staging (T3 vs. T1–T2) showed no significant association (P=0.198).Conclusion: Comprehensive evaluation of smoking history, surgical history, and lesion laterality is critical for recurrence risk stratification in SNIP management.
Keywords: Sinonasal inverted papilloma, Nasal endoscopic surgery, Recurrence, Smoking, Previous surgery
Received: 02 Dec 2024; Accepted: 20 Mar 2025.
Copyright: © 2025 LI, WANG and YIN. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
DeTao YIN, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
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