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CASE REPORT article

Front. Oncol.

Sec. Surgical Oncology

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1537611

Telangiectatic osteosarcoma of the thoracic vertebra: a case report and literature review

Provisionally accepted
  • 1 甘肃中医药大学, 甘肃省, China
  • 2 甘肃省人民医院, 甘肃省, China
  • 3 清水县人民医院, 甘肃省, China

The final, formatted version of the article will be published soon.

    Telangiectatic osteosarcoma (TOS) is a rare high-grade malignant tumour found primarily in the metaphysis of long bones, but can also occur in the pelvis, spine and skull. Characterised by extensive vascular dilatation and aggressive behaviour, TOS often has a poor prognosis and may be misdiagnosed due to similarities with other lesions. This report presents a case of TOS of the thoracic vertebrae and reviews the relevant literature to enhance clinical awareness.A 44-year-old woman presented with chest and back pain of worsening over two months, accompanied by lower limb numbness and incomplete paralysis. Initial treatment for "low back pain" proved ineffective. Imaging showed osteolytic destruction at T10, which led to surgery, and the tumour was classified as Tomita type III. The tumour was surgically resected, showing vascular proliferation and malignant stromal cells, confirming the pathological diagnosis of TOS. However, she developed complications requiring further surgery for recurrent problems, where a haematoma was discovered. Despite interventions, the patient's condition deteriorated, leading to the diagnosis of pulmonary metastasis and eventual death three months after the second surgery.This case highlights the need for increased awareness and accurate diagnosis of TOS, particularly in atypical presentations.

    Keywords: Telangiectatic osteosarcoma, Thoracic Vertebrae, case report, literature review, Bone tumors

    Received: 01 Dec 2024; Accepted: 28 Mar 2025.

    Copyright: © 2025 Wang, Xirong, xue, Zhang, li, Qilong, Gou, 周, Xing and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    wen xue, 甘肃省人民医院, 甘肃省, China
    guoquan li, 清水县人民医院, 甘肃省, China

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