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CASE REPORT article
Front. Oncol.
Sec. Hematologic Malignancies
Volume 15 - 2025 |
doi: 10.3389/fonc.2025.1537301
Mast cell leukaemia:a rare case report and Literature Review
Provisionally accepted- Department of Oncology and Hematology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China, Beijing, China
Mast cell leukemia (MCL) is an extremely rare and aggressive hematologic malignancy, characterized by a poor prognosis and short survival. Currently, no standardized treatment guidelines have been established. This study presents the clinical data of a patient with primary MCL accompanied by C-findings, and analyzes the clinical features, diagnostic challenges, and therapeutic approaches for this disease through a comprehensive review of the relevant literature.Furthermore, the study discusses current perspectives on research developments in MCL. By increasing clinical awareness of MCL, this work aims to provide valuable insights and references for clinicians in the diagnosis and management of this challenging condition.
Keywords: Mast cell leukemia, systemic mastocytosis, Rare Diseases, Clinical case reports, C-findings
Received: 30 Nov 2024; Accepted: 03 Feb 2025.
Copyright: © 2025 Tian, Yan, Shen, Fan and Tian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Lu Tian, Department of Oncology and Hematology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China, Beijing, China
Yang Shen, Department of Oncology and Hematology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China, Beijing, China
Qiuyue Fan, Department of Oncology and Hematology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China, Beijing, China
Shaodan Tian, Department of Oncology and Hematology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China, Beijing, China
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