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CASE REPORT article
Front. Oncol.
Sec. Skin Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1529976
DEB-TACE Combined with ICI for Advanced Squamous Cell Carcinoma of the Skin: A Case Report
Provisionally accepted- 1 Department of Oncology, Yanbian University Hospital, Yanji, China
- 2 Department of Interventional Radiotherapy, The Affiliated Hospital of Yanbian University, Yanji, Jilin Province, China
We report the case of an older female patient with squamous cell carcinoma of the skin, cTXN1M0, who initially presented with a mass of approximately 4.5 cm in diameter in the left temporal region, which had a tendency to break and bleed. Given the patient's poor general status and ECOG score of grade 2, it was considered that she could not tolerate systemic chemotherapy. Therefore, we applied drug-eluting beads transarterial chemoembolization combined with immune checkpoint inhibitors to treat this patient and unexpectedly found that this regimen resulted in complete classified remission and in partial pathological response without significant adverse events.
Keywords: DEB-TACE, ICI, CSCC, Complete remission, case report
Received: 20 Dec 2024; Accepted: 31 Mar 2025.
Copyright: © 2025 Piao, Wu, Piao, Kang, Jin, Xu and Jin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Longzhen Piao, Department of Oncology, Yanbian University Hospital, Yanji, China
Dehao Jin, Department of Interventional Radiotherapy, The Affiliated Hospital of Yanbian University, Yanji, Jilin Province, China
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