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CASE REPORT article
Front. Oncol.
Sec. Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1524974
This article is part of the Research Topic Innovative Approaches in Chemotherapy and Immunotherapy for Gastroenteropancreatic Neuroendocrine Carcinoma View all 3 articles
Rare Case Report: Primary Small-Cell Neuroendocrine Carcinoma of the Gallbladder
Provisionally accepted- Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China
Gallbladder cancer (GBC) accounts for 1.7% of all cancer-related deaths [1] . Neuroendocrine carcinoma of the gallbladder (GB-NEC) is a rare subtype of GBC that is more malignant than GBC [2- 4] . Small-cell neuroendocrine carcinoma of the gallbladder (GB-SCNEC) is a rare malignant tumor with a low incidence. To date, no universally accepted or satisfactory treatment exists. This case report details the clinical presentation, diagnostic process, and treatment strategy of a patient with GB-SCNEC. The analysis of this rare case is intended to provide clinicians with diagnostic and therapeutic insights for future research.
Keywords: Gallbladder, Small-cell neuroendocrine carcinoma, case report, diagnosis, Treatment
Received: 08 Nov 2024; Accepted: 03 Mar 2025.
Copyright: © 2025 Wang, Li, Han and Tian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Hu Tian, Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China
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