Pin Wang Mancai Wang Yongyong Liu ^*

• Lanzhou University Second Hospital, Lanzhou, China

Hemolymphangioma is a rare benign tumor. With only 12 reported cases in the pancreas as ofreports pancreatic cases until May 2024. We presentreport an invasived and giant hemolymphangioma of the pancreas in a young man who experiencedwith abdominal pain and left epigastric distension for approximatelyabout 10 days. Imaging studies revealed a large cystic tumor located in the body and tail of pancreas, which was compressing the partial lesser curvature of gastric and spleen, with displaying a "beaver tail" liver appearance on CT scans. AfterFollowing surgery, He was diagnosed with hemolymphangioma of the pancreas, and there were no signs of recurrence upon follow-up. We conclude that diagnosing hemolymphangioma of the pancreas can be challenging. Whenever possible, radical surgical resection should be performed, and long-term follow-up is essentialalso important. Key Words: pancreas； hemolymphangioma； surgery； cystic tumor； beaver tail liver； 1. INTRODUCTION Hemolymphangioma is a mixed malformation involving of lymphatic vessels and venules, primarily foundoccuring in the head and neck [1], and less commonlyrarely in the pancreas. It is classified asconsidered a rare primary cystic tumor. According to the literature, Hemolymphangioma hemolymphangioma of the pancreas account for approximately 0.1% of all pancreatic tumors [2]. The mainmajor symptoms and signs associated with hemolymphangioma include the presence of abdominal mass and distension, Which which can be challenging to distinguish difficult to differentiate from other pancreatic tumors, leading to potential misdiagnosis.and be misdiagnosed sometimes. Most cases are identifieddetected throughby imaging examination and confirmed by pathological analysis. In thisthe present study, we reported a case of an invasive and giant hemolymphangioma of the pancreas in a 24-year-old man.A 24-year-old male was admitted to our hospital with abdominal pain and left epigastric distension that lasted approximately 10 days. Physical examination revealed deep tenderness in the left upper abdomen. Laboratory data, including renal and liver function tests, complete blood count, urine and stool routine examinations, and tumor markers such as CA19-9, CEA and CA12-5 were all within normal ranges. The ultrasonography and CT scan findings indicated a large cystic tumor located in the body and tail of pancreas, which was compressing the partial lesser curvature of