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CASE REPORT article

Front. Oncol.
Sec. Neuro-Oncology and Neurosurgical Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1519842

PAEDIATRIC EXTRA-AXIAL MYXOPAPILLARY EPENDYMOMA: WHAT TO EXPECT? CASE REPORT AND LITERATURE REVIEW

Provisionally accepted
Roberto Lo Piccolo Roberto Lo Piccolo 1,2*Maria Chiara Cianci Maria Chiara Cianci 2Iacopo Sardi Iacopo Sardi 3Marco Di Nicola Marco Di Nicola 3Anna Maria Buccoliero Anna Maria Buccoliero 4Chiara Caporalini Chiara Caporalini 4Antonino Morabito Antonino Morabito 2,5
  • 1 Azienda Ospedaliera Universitaria Meyer IRCCS - Firenze, Florence, Italy
  • 2 Department of Pediatric Surgery, IRCCS Meyer Children’s Hospital, Florence, Tuscany, Italy
  • 3 Neuro-Oncology Unit, Meyer Children's Hospital, Florence, Tuscany, Italy
  • 4 Pathology Unit, Meyer Children's Hospital, Florence, Tuscany, Italy
  • 5 Department of Neuroscience, Psychology, Drugs and Child Health Area, School of Psychology, University of Florence, Florence, Tuscany, Italy

The final, formatted version of the article will be published soon.

    Extra-axial ependymomas are not common, and myxopapillary ependymomas (MPE) is the most common tumor type among children, often mistaken for other sacral lesions. Although MPEs are classified as low-grade tumors, they are frequently relapsed with distant metastasis. Therefore, it is necessary to have a proper diagnosis and follow-up. The current report details a case of extra-axial MPE in a pediatric patient who was diagnosed with an indolent sacral mass that required surgical resection, as well as a review of the literature. The purpose is to emphasize the significance of diagnostic suspicion in identifying sacral soft tissue masses.

    Keywords: Paediatric, sacral soft tissue lesion, case report, Myxopapillary ependymoma, Extra-axial ependymomas

    Received: 30 Oct 2024; Accepted: 03 Jan 2025.

    Copyright: © 2025 Lo Piccolo, Cianci, Sardi, Di Nicola, Buccoliero, Caporalini and Morabito. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Roberto Lo Piccolo, Azienda Ospedaliera Universitaria Meyer IRCCS - Firenze, Florence, Italy

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