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CASE REPORT article

Front. Oncol.

Sec. Gastrointestinal Cancers: Gastric and Esophageal Cancers

Volume 15 - 2025 | doi: 10.3389/fonc.2025.1512964

Calcifying fibrous tumor of stomach: a rare case report of an upper gastrointestinal bleeding

Provisionally accepted
Ye Bao Long Ye Bao Long 1,2Zhong Cailiang Zhong Cailiang 2*
  • 1 Southern Medical University, Guangzhou, China
  • 2 Ganzhou People's Hospital, Ganzhou, Jiangxi Province, China

The final, formatted version of the article will be published soon.

    Calcifying fibrous tumour (CFT) is an uncommon benign fibrous neoplastic lesion that may manifest as singular or multiple tumours and usually occurs in children or young adults. CFT originates in the muscularis propria of the stomach and is a very rare disease. Here, we report a case of gastric CFT with upper gastrointestinal bleeding.A 39-year-old male was urgently referred to our hospital with haematemesis and melena that had developed over the course of 2 hours. Enhanced abdominal CT imaging revealed a nodular lesion, measuring approximately 3.2 × 2.1 × 1.6 cm, protruding from the posterior wall of the gastric body into the gastric lumen. The lesion exhibited scattered calcifications, smooth margins, and a CT attenuation value of 50 Hounsfield units (HU). Gastroscopic ultrasonography performed in the gastroenterology department revealed a semicircular submucosal mass with signs of active bleeding. Initially, the tumour was diagnosed as a gastrointestinal stromal tumour (GIST), and surgical intervention was undertaken due to ongoing haemorrhage. Postoperative histopathological examination confirmed the diagnosis of a gastric calcifying fibrous tumour (CFT).CFT originating from the muscularis propria of the stomach is exceptionally rare, and the case presented here mimicked a gastric submucosal tumour (SMTs),clinicians should consider this differentia diagnosis when evaluating patients with suspected cases.

    Keywords: Calcifying fibrous tumour, Stomach, Submucosal tumour, gastrointestinal bleeding, case report

    Received: 09 Dec 2024; Accepted: 11 Mar 2025.

    Copyright: © 2025 Bao Long and Cailiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhong Cailiang, Ganzhou People's Hospital, Ganzhou, Jiangxi Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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