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CASE REPORT article

Front. Oncol.
Sec. Genitourinary Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1480790

Challenges in Diagnosing and Managing Sarcomatoid Urothelial Carcinoma of the Renal Pelvis: A Case Report

Provisionally accepted
Jian Lei Jian Lei Wei Zhao Wei Zhao *Tao He Tao He *Hui Huang Hui Huang *Huayong Jian Huayong Jian *mei Zhang mei Zhang *Xike Luo Xike Luo *Xiaochuan Gong Xiaochuan Gong *Yan Wang Yan Wang *
  • First People’s Hospital of Zunyi, Zunyi, China

The final, formatted version of the article will be published soon.

    Sarcomatoid urothelial carcinoma of the renal pelvis is an extremely rare malignant tumor with a high risk of recurrence and metastasis and a poor prognosis.This case reports a 61-year-old male patient with renal pelvic sarcomatoid urothelial carcinoma who developed extensive lymph node metastasis 26 days after posterior laparoscopic radical nephrectomy for renal carcinoma, and the patient died on the 45th postoperative day, with the cause of death being advanced malignancy of the tumor.This case highlights the rapid progression of sarcomatoid urothelial carcinoma, and sarcomatoid variants should be identified as early as possible,with active multidisciplinary adjuvant therapy and closer follow-up when feasible.Retrospective analysis of this patient's treatment regimen and admission provides lessons for recognizing and aggressively managing this rare and fatal variant of urothelial carcinoma.

    Keywords: renal pelvis sarcomatoid urothelial carcinoma, rare disease, posterior laparoscopic radical nephrectomy for renal cancer, Pathology, diagnosis, prognosis

    Received: 14 Aug 2024; Accepted: 07 Feb 2025.

    Copyright: © 2025 Lei, Zhao, He, Huang, Jian, Zhang, Luo, Gong and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Wei Zhao, First People’s Hospital of Zunyi, Zunyi, China
    Tao He, First People’s Hospital of Zunyi, Zunyi, China
    Hui Huang, First People’s Hospital of Zunyi, Zunyi, China
    Huayong Jian, First People’s Hospital of Zunyi, Zunyi, China
    mei Zhang, First People’s Hospital of Zunyi, Zunyi, China
    Xike Luo, First People’s Hospital of Zunyi, Zunyi, China
    Xiaochuan Gong, First People’s Hospital of Zunyi, Zunyi, China
    Yan Wang, First People’s Hospital of Zunyi, Zunyi, China

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