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CASE REPORT article
Front. Oncol.
Sec. Surgical Oncology
Volume 15 - 2025 |
doi: 10.3389/fonc.2025.1474481
The occurrence of dermatomyositis following resection of thyroid cancer and breast cancer: a case report and review of literature
Provisionally accepted- Yantai Yuhuangding Hospital, Yantai, China
Background: Dermatomyositis is an idiopathic inflammatory myopathy and occurs as a paraneoplastic syndrome. Here, we report an unusual case of dermatomyositis that developed in a patient after the resection of thyroid cancer and breast cancer. The intercorrelation between dermatomyositis and neoplastic disorders was discussed.Case presentation: A 60-year-old female farmer was diagnosed with thyroid cancer and breast cancer and then developed dermatomyositis after two curative surgeries and adjuvant chemotherapy. Dermatomyositic symptoms occurred after the fifth cycle of adjuvant chemotherapy for breast cancer and deteriorated progressively. Case history, imaging, and laboratory data were reviewed. This patient subsequently received systemic immunosuppressant therapy and thus dermatomyositis gradually resolved.A combination of thyroid cancer and breast cancer is thought to be very rare, especially in patients who develop dermatomyositis after thyroidectomy and mastectomy. An extraordinary case was reported in this study. Potential mechanisms for the development of dermatomyositis and novel insights neoplastic autoimmune diseases were proposed.
Keywords: Dermatomyositis, thyroid cancer, breast cancer, Paraneoplastic syndrome, Autoimmunity
Received: 01 Aug 2024; Accepted: 03 Jan 2025.
Copyright: © 2025 Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Miaomiao Yang, Yantai Yuhuangding Hospital, Yantai, China
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