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CASE REPORT article

Front. Oncol.
Sec. Hematologic Malignancies
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1449966

Unusual Symptoms Reveal a Rare Splenic Lymphoma: A Case Report of PS-DLBCL with Neck and Shoulder Pain as the Initial Presentation

Provisionally accepted
Shifu Hu Shifu Hu 1,2*Yuanyuan Hao Yuanyuan Hao 3Xiangyu Liu Xiangyu Liu 2Hanbo Liu Hanbo Liu 2
  • 1 Tianjin Xiqing Hospital, Xiqing, China
  • 2 Department of General Surgery, Tianjin Xiqing Hospital, Tianjin,china, Tianjin, China
  • 3 Department of Geriatrics, Tianjin Xiqing Hospital, Tianjin, China, Tianjin, China

The final, formatted version of the article will be published soon.

    The rare occurrence of diffuse large B-cell lymphoma (DLBCL) limited to the spleen presents difficulties in diagnosis.A case report details a patient whose initial symptoms were neck and shoulder pain, subsequently diagnosed as spontaneous spleen rupture, a rare complication of primary splenic lymphoma.Following a splenectomy, the patient was confirmed to have primary splenic DLBCL and made a good postoperative recovery.This report highlights the diagnostic dilemmas in atypical presentations, where neck and shoulder pain may be the only early sign of a neglected spleen rupture, lacking typical symptoms of the underlying disease.In cases of patients who are not stable, the recommended first imaging method is a focused assessment using sonography for trauma (FAST), as CT scans have a high level of sensitivity.Treatment is determined by hemodynamic status, with conservative management for stable patients and surgical intervention for unstable patients.The importance of recognizing spontaneous spleen rupture as a critical yet uncommon possibility in acute abdominal cases, especially in instances of primary splenic DLBCL, is emphasized in the report.

    Keywords: Spontaneous splenic rupture, Primary splenic diffuse large B-cell lymphoma, Splenectomy, Kehr's sign, case report

    Received: 16 Jun 2024; Accepted: 13 Jan 2025.

    Copyright: © 2025 Hu, Hao, Liu and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Shifu Hu, Tianjin Xiqing Hospital, Xiqing, China

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