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ORIGINAL RESEARCH article
Front. Oncol.
Sec. Head and Neck Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1441726
Knowledge, attitudes, and practices regarding the postoperative management and TSH suppression therapy among patients with thyroid cancer
Provisionally accepted- The Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
Background: Patient adherence to thyroid-stimulating hormone (TSH) suppression therapy is crucial for optimizing prognosis.Methods: This study aimed to examine the knowledge, attitude, and practice (KAP) toward TSH suppression therapy among patients. This cross-sectional study was conducted at our Hospital between March 2023 and October 2023 and included patients receiving TSH suppression therapy. A self-designed questionnaire was employed to collect their demographic characteristics and KAP. The analysis included 528 valid questionnaires.Results: The mean knowledge, attitude, and practice scores were 11.66±5.82 (possible range: 0-22), 33.31±4.97 (possible range: 0-40), and 24.46±3.46 (possible range: 0-34), respectively, indicating poor knowledge, favorable attitudes, and moderate practice. The knowledge scores were correlated to the attitude (r=0.399, P<0.001) and practice (r=0.401, P<0.001) scores, while the attitude scores were correlated to the practice scores (r=0.512, P<0.001). The structural equation modeling revealed that knowledge directly influenced attitude (β=0.34, P<0.001) and practice (β=0.13, P<0.001) and indirectly influenced practice through attitude (β=0.10, P<0.001). Conclusions: Patients receiving TSH suppression therapy in Zhanjiang demonstrated poor knowledge, favorable attitudes, and moderate practices toward TSH suppression therapy.
Keywords: knowledge, Attitude, Practice, thyroid cancer, thyroid-stimulating hormone, Cross-sectional study
Received: 31 May 2024; Accepted: 20 Feb 2025.
Copyright: © 2025 Wu, Zhang, Qin, Chen and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Tuo Xu, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, China
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