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ORIGINAL RESEARCH article

Front. Oncol.
Sec. Cancer Epidemiology and Prevention
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1440747
This article is part of the Research Topic Circadian Rhythm and Health View all articles

The Effect of Locomotive Syndrome on the Trajectory of Sleep Disturbance in Geriatric Oncology Inpatients

Provisionally accepted
Yu-Ling Yang Yu-Ling Yang 1Hui Su Hui Su 1Hui Lu Hui Lu 1Jing Wang Jing Wang 1Yu-Qing Zhou Yu-Qing Zhou 1Ling Li Ling Li 1Hui Yu Hui Yu 1Yan Lv Yan Lv 2Ying Chen Ying Chen 1*
  • 1 Department of Oncology, Affiliated Hospital of Jiangnan University, Wuxi, Liaoning Province, China
  • 2 Taihu Sanatorium of Jiangsu Province, Wuxi, Liaoning Province, China

The final, formatted version of the article will be published soon.

    Objective: To explore the developmental trajectory of sleep disturbance in geriatric oncology inpatients and assess the impact of locomotive syndrome (LS) on this trajectory. Methods: This longitudinal study enrolled 284 geriatric oncology inpatients through convenience sampling from August 2023 to February 2024 at the Oncology Center of the Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, China. Sleep quality was monitored for seven days following admission (T0-T6) using a wrist motion analyzer. The developmental trajectory of sleep disturbance was analyzed using the latent category growth model (LCGM). Patients were categorized into the LS group (n=177) and the non-LS group (n=107) based on the 25-question Geriatric Locomotive Function Scale (GLFS-25). Comparisons were made between the two groups regarding the distribution of sleep disturbance trajectories. Results: Three potential categories for the development trajectory of sleep disturbance in inpatients were identified: non-sleep disturbance, sleep disturbance improvement, and sleep disturbance persistence. The lowest sleep quality was observed on the second day after admission (T2). In the non-LS group, 40 cases (37.4%) experienced no sleep disturbance, 45 cases (42.1%) showed improvement, and 22 cases (20.6%) showed persistence of sleep disturbance. In the LS group, 32 cases (18.1%) experienced no sleep disturbance, 50 cases (28.2%) showed improvement, and 95 cases (53.7%) exhibited persistent sleep disturbance. Significant differences were found in the trajectory distribution of sleep disturbance between the two groups (P＜0.001). Conclusions: Sleep disturbance is prevalent in geriatric oncology inpatients, with an incidence of 74.6% (212/284), and is most severe on the third day after admission. Patients with LS exhibit lower overall sleep quality and a higher likelihood of persistent sleep disturbances. Keywords: Geriatric oncology inpatients; Sleep disturbance Trajectory; Locomotive syndrome.

    Keywords: Geriatric oncology inpatients, Sleep disturbance Trajectory, Locomotive syndrome, Cancer Epidemiology and Prevention, Circadian rhythm and health

    Received: 30 May 2024; Accepted: 14 Jan 2025.

    Copyright: © 2025 Yang, Su, Lu, Wang, Zhou, Li, Yu, Lv and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Ying Chen, Department of Oncology, Affiliated Hospital of Jiangnan University, Wuxi, Liaoning Province, China

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