Different exercise interventions on quality of sleep in breast cancer survivors-a network meta-analysis of randomized controlled trials

Qi Song ^1,2 Youkang Zhu ^1,2 Hai Liu ^1,2 Xiao Liu ^1,2 Liyun Xue ^1,2 Shaoying Yang ^1,2 Yujia Wang ^1,2 Zhangdong Jiang ^1,2 Xifang Liu ^1*

• ¹ Xi'an Honghui Hospital, Xi'an, Shaanxi Province, China
• ² Xi'an Physical Education University, Xi'an, China

Introduction： Breast cancer is currently the most prevalent cancer globally; however, it generally has a favorable prognosis and is linked to a high survival rate. While effective treatments can extend survival and mitigate associated side effects, not all survivors are exempt from complications.Notably, a significant proportion of survivors experience sleep disorders following surgery, which can severely impact their quality of life. Exercise is frequently recommended as a nonpharmacological intervention to enhance sleep quality among breast cancer survivors and may also play a role in reducing recurrence rates. Recognizing that various forms of exercise may yield different outcomes in addressing sleep disorders in this population, we conducted a network review meta-analysis to assess the effectiveness of diverse exercise modalities for breast cancer survivors suffering from sleep disturbances. Methods: We searched four electronic databases for randomized controlled trials of individuals diagnosed breast cancer with sleep disorders by different exercise therapy. The primary outcomes included Yoga, Pilates, Qigong, Tai Chi, Walking, Dance, Resistance training, Football, Virtual reality therapy, Activity change exercise, Software-guided exercises. The methodological quality of the included studies was assessed using the Cochrane Bias risk Assessment tool, and network metaanalysis was performed using Stata15 software. The review was pre-registered (PROSPERO ID: