Skip to main content

SYSTEMATIC REVIEW article

Front. Oncol.
Sec. Gastrointestinal Cancers: Colorectal Cancer
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1514581
This article is part of the Research Topic Nanomaterials for Cancer Diagnosis and Treatment View all articles

Mapping the intellectual structure and emerging trends on nanomaterials in colorectal cancer: A bibliometric analysis from 2003 to 2024

Provisionally accepted
Man Lu Man Lu 1Yi Liu Yi Liu 1Jin Zhu Jin Zhu 1*Jiarong Shang Jiarong Shang 1Lu Bai Lu Bai 2*Zhichao Jin Zhichao Jin 2Yue Hu Yue Hu 2*Zheng Xia Zheng Xia 2*Jun Qian Jun Qian 2*
  • 1 Nanjing University of Chinese Medicine, Nanjing, China
  • 2 Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Liaoning Province, China

The final, formatted version of the article will be published soon.

    Colorectal cancer (CRC) is one of the most prevalent malignant tumors worldwide. Current therapeutic strategies for CRC have limitations, while nanomaterials show significant potential for diagnosing and treating CRC. This study utilizes bibliometric analysis to evaluate the current status and trends in this field.Research on nanomaterials in CRC from 2003 to 2024 was retrieved from the Web of Science Core Collection (WOSCC). Tools such as CiteSpace, VOSviewer, RStudio, GraphPad Prism, and Excel were used to analyze trends and hotspots, covering publication trends, countries, institutions, authors, journals, co-citation analysis, and keywords. Visual maps were created to forecast future developments.The analysis includes 3,683 publications by 17,261 authors from 3,721 institutions across 100 countries/regions, published in 840 journals. Global publications have steadily increased, particularly since 2018. China leads in publication volume and citations, with six of the top ten research institutions and seven of the ten most cited authors, while the United States excels in citation impact and academic centrality. Both countries currently dominate the field, underscoring the urgent need for enhanced international collaboration. Ramezani M and Abnous K lead in publication volume and H-index, while Siegel RL is highly cited. The International Journal of Nanomedicine has the highest publication volume, while the Journal of Controlled Release is the most cited. In addition to "colorectal cancer" and "nanoparticles," the most common keyword is "drug delivery." Emerging research areas such as "metal-organic frameworks (MOFs)" and "green synthesis" are gaining attention as leading hotspots.This study offers an in-depth analysis of the application of nanomaterials in CRC, promoting interdisciplinary collaboration and advancing scientific progress in this field.

    Keywords: colorectal cancer, nanomaterial, bibliometric analysis, visualization, R-bibliometrix, Research trends

    Received: 21 Oct 2024; Accepted: 16 Dec 2024.

    Copyright: © 2024 Lu, Liu, Zhu, Shang, Bai, Jin, Hu, Xia and Qian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Jin Zhu, Nanjing University of Chinese Medicine, Nanjing, China
    Lu Bai, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Liaoning Province, China
    Yue Hu, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Liaoning Province, China
    Zheng Xia, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Liaoning Province, China
    Jun Qian, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Liaoning Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.