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MINI REVIEW article

Front. Oncol.
Sec. Head and Neck Cancer
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1510443

Diagnosis Progress of Carcinoma of Unknown Primary (CUP)

Provisionally accepted
yun  qiao yun qiao 1Mei  Wang Mei Wang 2kaiyuan  hui kaiyuan hui 2Xiaodong  Jiang Xiaodong Jiang 2*
  • 1 Lianyungang Clinical Medical College, Nanjing Medical University, Lianyungang, China
  • 2 The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, China

The final, formatted version of the article will be published soon.

    Carcinoma of unknown primary (CUP) is a common and complex type of tumor in clinical practice, where the primary site cannot be determined through conventional diagnostic methods, posing significant challenges for clinical diagnosis and treatment. In recent years, advancements in gene expression profiling and genetic testing technologies have provided new perspectives for CUP research, driving progress in this field. By analyzing gene expression profiles, researchers can more effectively identify the tissue origin of tumors, thereby improving diagnostic accuracy. At the same time, the potential application of genetic testing is continuously being explored, offering new possibilities for personalized treatment. This article aims to discuss the latest advancements in the diagnosis of CUP, analyze the importance of gene expression profiling and genetic testing in tumor origin identification and their clinical applications, and summarize current research progress and future research directions, with the goal of providing a theoretical basis for the early diagnosis and treatment of CUP.

    Keywords: Carcinoma of unknown primary, Gene Expression Profiling, Genetic Testing, personalized treatment, traceable diagnosis

    Received: 13 Oct 2024; Accepted: 12 Nov 2024.

    Copyright: © 2024 qiao, Wang, hui and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Xiaodong Jiang, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.