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REVIEW article

Front. Oncol.
Sec. Genitourinary Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1503116
This article is part of the Research Topic Advances in the Treatment of Urothelial Carcinoma View all 5 articles

Female urethral diverticular carcinoma: a case report and review of the literature

Provisionally accepted
Li Dan Li Dan 1*Yang Xu Yang Xu 1hua Fan Meng hua Fan Meng 2
  • 1 Chengdu Fifth People's Hospital, Chengdu, China
  • 2 The First People's Hospital of Fuyang District of Hangzhou, Hangzhou, Jiangsu Province, China

The final, formatted version of the article will be published soon.

    To investigate the etiology, clinical manifestations, treatment methods, and prognosis of urethral diverticulum cancer to enhance understanding of this disease. Methods: This paper reports a case of urethral diverticulum cancer with "hematuria and dysuria" as the main clinical manifestations. The case is discussed in conjunction with relevant literature. Results: The patient initially presented to the gynecology department due to postmenopausal bleeding but was not diagnosed with the disease. Subsequently, the patient developed hematuria and dysuria and was referred to the urology department. MRI indicated urethral diverticulum-like changes with suspected tumorous lesions. Cystourethroscopic biopsy confirmed urethral diverticulum cancer. The patient underwent urethrectomy, and postoperative pathological diagnosis was poorly differentiated urothelial adenocarcinoma. Conclusion: Urethral diverticulum cancer is a rare and highly aggressive malignant tumor of the urethra with a poor prognosis. The onset of urethral diverticulum cancer is concealed, and its clinical manifestations are nonspecific and diverse. Preoperative diagnosis is challenging, and imaging studies and cystourethroscopy are the primary preoperative diagnostic methods for urethral diverticulum cancer. Pathology and immunohistochemistry serve as the basis for confirmation of diagnosis.Currently, there is no unified treatment protocol for female urethral diverticulum cancer internationally. For female patients with urethral

    Keywords: Cancer, clinical manifestations, Treatment methods, Diverticulum, Urethra

    Received: 28 Sep 2024; Accepted: 16 Dec 2024.

    Copyright: © 2024 Dan, Xu and Meng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Li Dan, Chengdu Fifth People's Hospital, Chengdu, China

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