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MINI REVIEW article

Front. Oncol.
Sec. Head and Neck Cancer
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1502283
This article is part of the Research Topic Exploring the Role of Exosomes in Cancer Metastasis View all articles

Exosomes in Oral Squamous Cell Carcinoma (OSCC): Functions, Challenges, and Potential Applications

Provisionally accepted
Bo Zhao Bo Zhao *Zuntai Li Zuntai Li *Ronghua Li Ronghua Li *
  • Tianjin First Central Hospital, Tianjin, China

The final, formatted version of the article will be published soon.

    Oral squamous cell carcinoma (OSCC) accounts for approximately 90% of all oral cancers, significantly impacting the survival and quality of life of patients. Exosomes, small extracellular vesicles released by cells, play a crucial role in intercellular communication in cancer. Nevertheless, their function and mechanism in OSCC remain elusive. Search Pubmed, Web of Science, and Cochrane Library using keywords OSCC, exome, diagnosis, and treatment to review the research progress of exome in OSCC. Based on these results, this review starting from the biosynthesis, structure, and contents of exosomes, elaborates on the research progress of exosomes in the diagnosis and treatment of OSCC. It explores the potential of exosomes in the diagnosis and treatment of OSCC, and briefly describes the challenges researchers currently face.

    Keywords: extracellular vesicles, Biological characteristics, OSCC, oncology, Exosomes

    Received: 26 Sep 2024; Accepted: 05 Dec 2024.

    Copyright: © 2024 Zhao, Li and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Bo Zhao, Tianjin First Central Hospital, Tianjin, China
    Zuntai Li, Tianjin First Central Hospital, Tianjin, China
    Ronghua Li, Tianjin First Central Hospital, Tianjin, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.