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CASE REPORT article

Front. Oncol.
Sec. Gynecological Oncology
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1499403

A case report and literature review: leiomyosarcoma or perivascular epithelioid cell neoplasm?

Provisionally accepted
Zheng Chen Zheng Chen Xuan Zheng Xuan Zheng Qin Lin Qin Lin *
  • International Peace Maternity and Child Health Hospital, Shanghai, China

The final, formatted version of the article will be published soon.

    The distinction between uterine leiomyosarcoma (uLMS) and perivascular epithelioid cell neoplasm (PEComa) has been quite challenging. Here we report a 39-year-old woman who underwent hysteromyomectomy. Intraoperative frozen section pathological examination revealed that the mass was likely to be mesenchymal malignancy. After consultation with her family, the total hysterectomy and bilateral salpingo-oophorectomy was performed. Postoperative pathology suggested leiomyosarcoma, but malignant PEComa cannot be completely excluded. Combining the present case and prior studies, we summarized the clinical manifestations, pathologic features, genomic characterization, and treatment of LMS and PEComa.

    Keywords: case report, Uterine neoplasm, Leiomyosarcoma, Perivascular epithelioid cell neoplasm, diagnosis

    Received: 20 Sep 2024; Accepted: 04 Dec 2024.

    Copyright: © 2024 Chen, Zheng and Lin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Qin Lin, International Peace Maternity and Child Health Hospital, Shanghai, China

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