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CASE REPORT article

Front. Oncol.
Sec. Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1495517

A rare case of intragastric Metastasis After Liver Transplantation for Liver Cancer

Provisionally accepted
Youfeng Xue Youfeng Xue 1*Baojie Shi Baojie Shi 2*Jianfa Zhong Jianfa Zhong 2*Guimei Wang Guimei Wang 3*Jie Wang Jie Wang 3*Wenbin An Wenbin An 2Yunyun Qian Yunyun Qian 2*Zhaojie Su Zhaojie Su 3Zhihai Peng Zhihai Peng 3*Hao Li Hao Li 3*
  • 1 Fuqing Hospital, Fuqing, China
  • 2 Xiamen University, Xiamen, Fujian Province, China
  • 3 Xiang'an Hospital, Xiamen University, Xiamen, Fujian Province, China

The final, formatted version of the article will be published soon.

    A 13-year-old boy was admitted to Xiang'an Hospital of Xiamen University due to HBV-related liver cancer. Intrahepatic metastasis was considered to occur by CT scan.A gastroscope revealed esophagogastric variceal bleeding, and later, the patient underwent a successful liver transplantation. Fourteen months posttransplant, chest CT indicated lung metastasis, and the patient underwent thoracoscopic radical resection of lung cancer. Twenty-one months posttransplant, gastroscopy revealed a gastric fundus tumor growing into the gastric cavity. Proximal gastrectomy was performed, and pathology indicated moderately to poorly differentiated carcinoma without invasion of serosa, suggesting the first study to report HCC metastasis to the stomach lumen without invasion of serosa after LT. Currently, the alpha-fetoprotein (AFP) level of the patient has dropped below normal.

    Keywords: Hepatocellular Carcinoma, Intragastric Metastasis, liver cancer, Liver Transplantation, pediatric liver transplantation

    Received: 12 Sep 2024; Accepted: 19 Nov 2024.

    Copyright: © 2024 Xue, Shi, Zhong, Wang, Wang, An, Qian, Su, Peng and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Youfeng Xue, Fuqing Hospital, Fuqing, China
    Baojie Shi, Xiamen University, Xiamen, 361005, Fujian Province, China
    Jianfa Zhong, Xiamen University, Xiamen, 361005, Fujian Province, China
    Guimei Wang, Xiang'an Hospital, Xiamen University, Xiamen, Fujian Province, China
    Jie Wang, Xiang'an Hospital, Xiamen University, Xiamen, Fujian Province, China
    Yunyun Qian, Xiamen University, Xiamen, 361005, Fujian Province, China
    Zhihai Peng, Xiang'an Hospital, Xiamen University, Xiamen, Fujian Province, China
    Hao Li, Xiang'an Hospital, Xiamen University, Xiamen, Fujian Province, China

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